Get ready to dive into a groundbreaking development in neuroscience research! Bruker’s xView Module Revolutionizes Imaging for Neuroscientists.
At the cutting-edge Neuroscience 2025 conference, Bruker Corporation unveiled a game-changer: the xView Module for their Ultima 2Pplus multiphoton microscopes. This innovative upgrade promises to transform the way we explore the brain’s intricate neural networks.
The xView Module is a patent-pending masterpiece, designed to enhance the field-of-view (FOV) of Ultima systems by an impressive 2.5 times. This means researchers can now capture high-resolution images of neural activity across larger brain areas, without sacrificing speed or sensitivity. It’s like having a super-powered microscope that reveals the brain’s secrets with unprecedented clarity.
But here’s where it gets even more exciting: the xView Module isn’t just about bigger pictures. It’s engineered to meet the complex demands of systems neuroscience research. By visualizing expansive neural circuits alongside optogenetic activation, researchers can delve into the brain’s intricate input-output relationships and manipulate widespread neuronal networks. This unprecedented commercial pairing of vast imaging FOV with large-volume optogenetics opens up new avenues for understanding brain-wide connectivity and function.
And this is the part most people miss: the xView Module is a game-changer for studying neurological disorders. Its ability to conduct broader imaging studies of epileptic activity across the brain and circuit mapping for Alzheimer’s and Parkinson’s diseases is a huge step forward. It’s like having a powerful tool to unravel the mysteries of these complex conditions.
Associate Professor Caroline Runyan from the University of Pittsburgh’s Department of Neuroscience is already raving about the xView Module. She’s been using it to study the spatial and temporal properties of circuits across cortical brain regions, and the increased FOV has been a game-changer for her research.
“I’m thrilled to combine this new capability with 3D optogenetics on our Ultima2Pplus microscopes,” she said.
The xView Module truly unlocks a new scale of imaging for neuroscience, pushing the boundaries of what’s possible. By expanding the FOV while maintaining optical precision, Bruker continues to build upon the success and research capabilities of the Ultima platform.
Xiaomei Li, Ph.D., Vice President and General Manager of Bruker’s Fluorescence Microscopy Business, sums it up perfectly: “By expanding the FOV while maintaining optical precision, we are continuing to build upon the Ultima platform’s success and research capabilities and push the limits of imaging instrumentation. We are looking forward to seeing the benefits and discoveries this helps bring to the scientific community.”
The xView Module integrates seamlessly with Ultima’s xCore FPGA electronics, offering flexibility to record across larger areas at speeds faster than video rate or with ultra-high fidelity up to 8K resolution. This combination provides the market’s most comprehensive solution for mesoscale neural circuit studies, without compromising speed or resolution.
So, there you have it – Bruker’s xView Module is a game-changer for neuroscience research. It’s an exciting development that promises to unlock new insights into the brain’s intricate workings.
What do you think? Will the xView Module revolutionize neuroscience research? Share your thoughts and let’s discuss the potential impact of this innovative technology!